Project Overview:

Research Ideas/Gaps in Knowledge

Ongoing Projects: Additional Background 

Active Site & Catalysis, Mobile Loop & Specificity

                Background Information to the project area

Ongoing Projects (Access to these pages requires an additional password: contact Ellis Bell (jbell@sandiego.edu) if you are interested in joining this group.)

Manuscript Plans & Writing Teams

Standardized Data Repository

Schools Teaching CUREs based on this project areas: University of San Diego, St John Fisher College

Available Biologics: wt Watermelon Glyoxysomal Malate Dehydrogenase, Active Site Loop mutants of Watermelon Glyoxysomal Malate Dehydrogenase

Relevant Publications:

The Role of the Flexible Loop in Substrate Recognition and Catalysis in Malate Dehydrogenase, Alexandra Roessling, Ellis Bell, Jessica Bell: First published: 18 April 2020,

Combining Computational and Experimental approaches to investigate the catalytic mechanism of glyoxysomal Malate Dehydrogenase, Hugo Guterres, Shannon Hedrick, Ellis Bell, First published: 01 April 2011

Crystallographic Studies of Glyoxysomal Malate Dehydrogenase Mutants D193N and H220Q, Wazo Myint, Ellis Bell, First published: 07 March 2006

Probing the Mobile Loop Region of Malate Dehydrogenase (MDH) for Potential Pathogenic Allosteric Inhibitor Drug Target. Sharon Shania (Bell Lab)