Mobile Loop & Specificity

                Background Information to the project area

 Current Focus:

                                Watermelon Glyoxysomal Malate Dehydrogenase

                                Plasmodium falciparum Malate Dehydrogenase

 Schools Teaching CUREs based on this project areas

                                University of San Diego

                                St John Fisher College

 Available Biologics

                                wt Watermelon Glyoxysomal Malate Dehydrogenase

                                Active Site Loop mutants of Watermelon Glyoxysomal Malate Dehydrogenase

                                Wt Plasmodium falciparum Malate Dehydrogenase

Publications:

The Role of the Flexible Loop in Substrate Recognition and Catalysis in Malate Dehydrogenase, Alexandra Roessling, Ellis Bell, Jessica Bell: First published: 18 April 2020, https://doi.org/10.1096/fasebj.2020.34.s1.05403

Combining Computational and Experimental approaches to investigate the catalytic mechanism of glyoxysomal Malate Dehydrogenase, Hugo Guterres, Shannon Hedrick, Ellis Bell, First published: 01 April 2011, https://doi.org/10.1096/fasebj.25.1_supplement.536.2

Crystallographic Studies of Glyoxysomal Malate Dehydrogenase Mutants D193N and H220Q, Wazo Myint, Ellis Bell, First published: 07 March 2006, https://doi.org/10.1096/fasebj.20.5.A907-c